細胞名稱 |
人脊索瘤細胞U-CH1 |
英文名稱 |
U-CH1 |
形態特性 |
間充質細胞樣 |
生長特性 |
貼壁生長 |
種屬 |
人 |
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組織 |
脊柱;骶骨 |
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培養體系 |
80% mixture of Iscove's MDM and RPMI 1640 (at 4:1)+10% FBS+1% P/S 氣相:空氣,95%;CO2,5%。 溫度:37℃ |
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STR |
Amelogenin X,Y CSF1PO 10,11 D1S1656 16,16.3 D2S441 12,14 D2S1338 17,18 D3S1358 15 D5S818 11,12 D7S820 9,12 D8S1179 10,15 D10S1248 15 D12S391 17,22 D13S317 11,13 D16S539 12,13 D18S51 15 D19S433 14 D21S11 28,29 D22S1045 16 FGA 20,21 Penta D 11 Penta E 7,10 TH01 7 TPOX 8,11 vWA 17
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簡介 |
U-CH1 is the first human chordoma cell line. It exhibits chordoma-like characteristics and has molecular, genetic, and morphological features typical of chordoma. This cell line was established from a local recurrence of a sacrococcygeal chordoma after radiotherapy 4 years after initial surgery. Chordoma is a rare slow-growing tumor type, and U-CH1 is a relatively slow-growing cell line. U-CH1 has a heterogeneous morphology consisting of physaliferous cells with mcinous intercellular substance, which represent typical chordoma features. The cells overexpress the transcription factor T (Brachyury) that is the most specific marker for chordoma. This cell line was accessioned with the support of the Chordoma Foundation, a non-profit organization working to improve the lives of Chordoma patients by accelerating research to develop effective treatments for the chordoma disease |
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傳代方法 |
建議第一次1:2傳代 |
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凍存條件 |
90 FBS+10% DMSO, 推薦無血清凍存液 (CX001) |
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用途 |
僅限于科學研究,不可作為動物或人類疾病的治療產品使用。 |
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